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Associate Director / Director in Large Molecule Bioanalysis

工作地点:上海浦东         所属类型:DMPK         发布时间:2019-07-05

岗位描述:

Responsibility:

• Develop and validate immunoassays and cell-based assays to detect and quantify large molecule, biologics, neutralizing antibodies and antibody-drug conjugates in preclinical drug metabolism and pharmacokinetics studies.

• Build a team to design, develop, and validate the immunoassays such as enzyme-linked immunosorbent assay (ELISA), meso scale discovery (MSD), luminex, immunogenicity assays. Write and review study protocols and reports for assay development, validation and analysis.

• Supervise and train laboratory staff.

• Interact with clients in planning study proposals and quotations in response to client requests.

• Maintain close and effective communications with clients and report study progress in a timely manner.

任职资格:

• A Ph.D.(3-6 year working experience) or MS(10-15 year working experience) degree in pharmaceutical sciences, immunology, Biochemistry, Biology, Immunoassays, or a related field with 3-15 years of industrial experience in pharmaceutical and biotechnological companies, or contract research organizations.

• Industrial experience in assay development for large molecules quantitation in support of preclinical studies in drug metabolism (DM), pharmacokinetics (PK), toxicokinetics (TK), pharmacodynamics (PD), anti-drug antibody (ADA) and vaccine.

• Hands-on experience with ligand binding and cell-based assays in support of biologics and vaccine development in drug discovery and development.

• Experience with protein quantitation using LC-MS/MS platform is a plus

• Demonstrate capability and confidence to build, train and lead a group

• Good interpersonal communication skills, and excellent oral and written English skills